| 1 | These results define a biochemical mechanism by which the BRCA1 enzymatic activity regulates a key cellular process. PMID :17420471
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| 2 | As part of screening 283 ovarian cancer families for BRCA1 mutations, we used two different methods (mutation specific PCR and multiplex ligation-dependent probe amplification) to screen for a known rearrangement mutation L78833.1:g.44369_50449dup (ins6kbEx13). PMID :17397054
- Category : Gene- Mutation | Gene- Disease
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| 3 | Prediction of BRCA1/2 mutation status in patients with ovarian cancer from a hospital-based cohort. PMID :17413421
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| 4 | CONCLUSION: As the combination of a personal history of breast cancer and a family history of breast, ovarian, or uterine/endometrioid cancer had good predictive value for the presence of a pathogenic BRCA1/2 mutation, the presented prediction test is a useful instrument to identify those women eligible for DNA testing. PMID :17413421
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| 5 | This is the first report of a GCT in a BRCA2 mutation carrier; there was one previous report of an ovarian dysgerminoma in a BRCA1 carrier. PMID :17413983
- Category : Gene- Gene | Gene- Disease
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